The rare malformation holoprosencephaly: pathogenesis, association with pregestational diabetes and the possible link with food pollutants
Background. Holoprosencephaly is a rare (1/16,000 livebirths) and severe brain malformation occurring during early embryogenesis. The malformation originates from absent or incomplete forebrain division and is associated with altered embryonic patterning. Objectives. A narrative review to identify a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Istituto Superiore di Sanità
2023-12-01
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Series: | Annali dell'Istituto Superiore di Sanità |
Online Access: | https://annali.iss.it/index.php/anna/article/view/1619 |