Silibinin Improves TNF-α and M30 Expression and Histological Parameters in Rat Kidneys After Hepatic Ischemia/Reperfusion

Silibinin Improves TNF-α and M30 Expression and Histological Parameters in Rat Kidneys After Hepatic Ischemia/Reperfusion

Background: Remote kidney damage is a sequel of hepatic ischemia–reperfusion (I/R) injury. Silibinin is the main ingredient of the milk thistle plant seed extract with known antioxidant and hepatoprotective activity. Our study investigates the nephroprotective potential of intravenously administered...

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Bibliographic Details
Main Authors: Georgios Kyriakopoulos, Alexandra K. Tsaroucha, Georgia Valsami, Maria Lambropoulou, Nikolaos Kostomitsopoulos, Eirini Christodoulou, Zacharias Kakazanis, Constantinos Anagnostopoulos, Christos Tsalikidis, Constantinos E. Simopoulos
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Journal of Investigative Surgery
Subjects:
silibinin
ischemia-reperfusion injury
tnf-α
m30
renal damage
rat
Online Access:http://dx.doi.org/10.1080/08941939.2017.1308044

Internet

http://dx.doi.org/10.1080/08941939.2017.1308044

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