Graft-versus-host disease: establishing IL-33 as an important costimulatory molecule
Approximately half of patients with hematologic malignancy who are treated with allogeneic hematopoietic stem cell transplantation (alloHCT) experience graft-versus-host disease (GVHD), which has high mortality rates despite immunosuppressive therapy. IL-12 is known to drive donor T cells toward an...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Clinical Investigation
2022-06-01
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| Series: | The Journal of Clinical Investigation |
| Online Access: | https://doi.org/10.1172/JCI160692 |