Anxiolytic Activity and Brain Modulation Pattern of the α-Casozepine-Derived Pentapeptide YLGYL in Mice

Anxiolytic Activity and Brain Modulation Pattern of the α-Casozepine-Derived Pentapeptide YLGYL in Mice

α-Casozepine (α-CZP) is an anxiolytic-like bioactive decapeptide derived from bovine α<sub>s1</sub>-casein. The N-terminal peptide YLGYL was previously identified after proteolysis of the original peptide in an in vitro digestion model. Its putative anxiolytic-like properties were evalua...

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Bibliographic Details
Main Authors: Simon Benoit, Catherine Chaumontet, Jessica Schwarz, Céline Cakir-Kiefer, Audrey Boulier, Daniel Tomé, Laurent Miclo
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Nutrients
Subjects:
milk bioactive peptide
α-Casozepine
proteolytic fragments
anxiety
neuronal activity modulation
c-Fos
Online Access:https://www.mdpi.com/2072-6643/12/5/1497

Internet

https://www.mdpi.com/2072-6643/12/5/1497

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