Mechanisms underlying the methylglyoxal-induced enhancement of uridine diphosphate-mediated contraction in rat femoral artery

Although femoral artery dysfunctions, including aberrant vascular reactivity to vasoactive substances, are common in many chronic disorders, such as diabetes and hypertension, their inducible and/or progressive factors remain unclear. Methylglyoxal (MGO), a highly reactive dicarbonyl compound, has b...

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Bibliographic Details
Main Authors: Takayuki Matsumoto, Madoka Yoshioka, Aiko Yamada, Kumiko Taguchi, Tsuneo Kobayashi
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861322000597