Acute HDM exposure shows time-of-day and sex-based differences in the severity of lung inflammation and circadian clock disruption

Acute HDM exposure shows time-of-day and sex-based differences in the severity of lung inflammation and circadian clock disruption

Background: Asthma is a chronic inflammatory disease that shows a time-of-day response to variations in symptoms/severity. However, how the lung circadian clock influences time-of-day response and sex-based differences in house dust mite (HDM)-induced airway inflammation and remodeling has not been...

Full description

Bibliographic Details
Main Authors: Ashokkumar Srinivasan, PhD, Allan Giri, MS, Santhosh Kumar Duraisamy, MSc, Alexander Alsup, MS, Mario Castro, MD, MPH, Isaac Kirubakaran Sundar, PhD
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Airway inflammation
allergic asthma
circadian rhythms
cytokine/chemokine gating
house dust mite
Rev-erbαKO
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829323000802

Internet

http://www.sciencedirect.com/science/article/pii/S2772829323000802

Similar Items