A tissue-engineered model of the atherosclerotic plaque cap: Toward understanding the role of microcalcifications in plaque rupture

Rupture of the cap of an atherosclerotic plaque can lead to thrombotic cardiovascular events. It has been suggested, through computational models, that the presence of microcalcifications in the atherosclerotic cap can increase the risk of cap rupture. However, the experimental confirmation of this...

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Bibliographic Details
Main Authors: Imke Jansen, Hanneke Crielaard, Tamar Wissing, Carlijn Bouten, Frank Gijsen, Ali C. Akyildiz, Eric Farrell, Kim van der Heiden
Format: Article
Language:English
Published: AIP Publishing LLC 2023-09-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0168087