Antimalarial drugs disrupt ion homeostasis in malarial parasites

Antimalarial drugs disrupt ion homeostasis in malarial parasites

Plasmodium chabaudi malaria parasite organelles are major elements for ion homeostasis and cellular signaling and also target for antimalarial drugs. By using confocal imaging of intraerythrocytic parasites we demonstrated that the dye acridine orange (AO) is accumulated into P. chabaudi subcellular...

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Bibliographic Details
Main Authors: Marcos L Gazarini, Carlos AO Sigolo, Regina P Markus, Andrew P Thomas, Célia RS Garcia
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2007-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
malaria
Plasmodium chabaudi
calcium
chloroquine
artemisinin
acidic compartment
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000300012

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000300012

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