Deletion of the Imprinted <i>Phlda2</i> Gene Increases Placental Passive Permeability in the Mouse

Deletion of the Imprinted <i>Phlda2</i> Gene Increases Placental Passive Permeability in the Mouse

Genomic imprinting, an epigenetic phenomenon that causes the expression of a small set of genes in a parent-of-origin-specific manner, is thought to have co-evolved with placentation. Many imprinted genes are expressed in the placenta, where they play diverse roles related to development and nutrien...

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Bibliographic Details
Main Authors: Emily Angiolini, Ionel Sandovici, Philip M. Coan, Graham J. Burton, Colin P. Sibley, Abigail L. Fowden, Miguel Constância
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Genes
Subjects:
<i>Phlda2</i>
genomic imprinting
placenta
fetal growth
passive permeability
Online Access:https://www.mdpi.com/2073-4425/12/5/639

Internet

https://www.mdpi.com/2073-4425/12/5/639

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