NT-seq: a chemical-based sequencing method for genomic methylome profiling
Abstract DNA methylation plays vital roles in both prokaryotes and eukaryotes. There are three forms of DNA methylation in prokaryotes: N 6-methyladenine (6mA), N 4-methylcytosine (4mC), and 5-methylcytosine (5mC). Although many sequencing methods have been developed to sequence specific types of me...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-05-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-022-02689-9 |