A plant-produced Pfs25 VLP malaria vaccine candidate induces persistent transmission blocking antibodies against Plasmodium falciparum in immunized mice.

A plant-produced Pfs25 VLP malaria vaccine candidate induces persistent transmission blocking antibodies against Plasmodium falciparum in immunized mice.

Malaria transmission blocking vaccines (TBVs) are considered an effective means to control and eventually eliminate malaria. The Pfs25 protein, expressed predominantly on the surface of the sexual and sporogonic stages of Plasmodium falciparum including gametes, zygotes and ookinetes, is one of the...

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Bibliographic Details
Main Authors: R Mark Jones, Jessica A Chichester, Vadim Mett, Jennifer Jaje, Stephen Tottey, Slobodanka Manceva, Louis J Casta, Sandra K Gibbs, Konstantin Musiychuk, Moneim Shamloul, Joey Norikane, Valentina Mett, Stephen J Streatfield, Marga van de Vegte-Bolmer, Will Roeffen, Robert W Sauerwein, Vidadi Yusibov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3832600?pdf=render

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http://europepmc.org/articles/PMC3832600?pdf=render

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