Osteogenic CpG Oligodeoxynucleotide, iSN40, Inhibits Osteoclastogenesis in a TLR9-Dependent Manner

A CpG oligodeoxynucleotide (CpG-ODN), iSN40, was originally identified as promoting the mineralization and differentiation of osteoblasts, independent of Toll-like receptor 9 (TLR9). Since CpG ODNs are often recognized by TLR9 and inhibit osteoclastogenesis, this study investigated the TLR9 dependen...

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Bibliographic Details
Main Authors: Rena Ikeda, Chihaya Kimura, Yuma Nihashi, Koji Umezawa, Takeshi Shimosato, Tomohide Takaya
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/14/12/1572