Relationship between homologous recombination deficiency and clinical features of breast cancer based on genomic scar score

Relationship between homologous recombination deficiency and clinical features of breast cancer based on genomic scar score

Background: Homologous recombination deficiency (HRD) phenotype will sensitize tumors to poly (ADP-ribose) polymerases inhibitors and platinum. However, previous studies did not focus on the prevalence of HRD among Chinese breast cancer (BC) patients. Methods: One hundred and forty-seven BC patients...

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Bibliographic Details
Main Authors: Cong Feng, Yinbin Zhang, Fei Wu, Jia Li, Mengjie Liu, Wei Lv, Chaofan Li, Weiwei Wang, Qinghua Tan, Xiaoyu Xue, Xingcong Ma, Shuqun Zhang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Breast
Subjects:
Breast cancer
BRCA1/2
Homologous recombination deficiency
Genomic scar score
Clinical characteristics
Online Access:http://www.sciencedirect.com/science/article/pii/S096097762300437X

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http://www.sciencedirect.com/science/article/pii/S096097762300437X

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