Pseudo-Temporal Analysis of Single-Cell RNA Sequencing Reveals Trans-Differentiation Potential of Greater Epithelial Ridge Cells Into Hair Cells During Postnatal Development of Cochlea in Rats

Pseudo-Temporal Analysis of Single-Cell RNA Sequencing Reveals Trans-Differentiation Potential of Greater Epithelial Ridge Cells Into Hair Cells During Postnatal Development of Cochlea in Rats

The hair cells of the cochlea play a decisive role in the process of hearing damage and recovery, yet knowledge of their regeneration process is still limited. Greater epithelial ridge (GER) cells, a type of cell present during cochlear development that has the characteristics of a precursor sensory...

Full description

Bibliographic Details
Main Authors: Jianyong Chen, Dekun Gao, Junmin Chen, Shule Hou, Baihui He, Yue Li, Shuna Li, Fan Zhang, Xiayu Sun, Yulian Jin, Lianhua Sun, Jun Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
sc-RNA sequencing
pseudo-temporal analysis
cochlear basal membrane
greater epithelial ridge cells
hair cells
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.832813/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.832813/full

Similar Items