Acquired radioresistance in EMT6 mouse mammary carcinoma cell line is mediated by CTLA-4 and PD-1 through JAK/STAT/PI3K pathway

Acquired radioresistance in EMT6 mouse mammary carcinoma cell line is mediated by CTLA-4 and PD-1 through JAK/STAT/PI3K pathway

Abstract Cancer recurrence is often associated with the acquisition of radioresistance by cancer tissues due to failure in radiotherapy. The underlying mechanism leading to the development of acquired radioresistance in the EMT6 mouse mammary carcinoma cell line and the potential pathway involved wa...

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Bibliographic Details
Main Authors: Nur Fatihah Ronny Sham, Narimah Abdul Hamid Hasani, Nurhaslina Hasan, Muhammad Khalis Abdul Karim, Syed Baharom Syed Ahmad Fuad, Harissa Husainy Hasbullah, Mohammad Johari Ibahim
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29925-x

Internet

https://doi.org/10.1038/s41598-023-29925-x

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