Efficient support of virus-like particle assembly by the HIV-1 packaging signal
The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity. However, if no genomic RNA is present, Gag assembles into particles containing cellular mRNA...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/38438 |