Senescence Markers in Peripheral Blood Mononuclear Cells in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease

Senescence Markers in Peripheral Blood Mononuclear Cells in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease

Recent studies suggest that cellular senescence plays a role in Alzheimer’s Disease (AD) pathogenesis. We hypothesize that cellular senescence markers might be tracked in the peripheral tissues of AD patients. Senescence hallmarks, including altered metabolism, cell-cycle arrest, DNA damage response...

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Bibliographic Details
Main Authors: Felipe Salech, Carol D. SanMartín, Jorge Concha-Cerda, Esteban Romero-Hernández, Daniela P. Ponce, Gianella Liabeuf, Nicole K. Rogers, Paola Murgas, Bárbara Bruna, Jamileth More, María I. Behrens
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
cellular senescence
peripheral blood mononuclear cells
Alzheimer’s Disease
aMCI
aging
Online Access:https://www.mdpi.com/1422-0067/23/16/9387

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https://www.mdpi.com/1422-0067/23/16/9387

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