SQLE promotes osteosarcoma progression via activating TGFβ/SMAD signaling pathway

Background: The prognosis of advanced osteosarcoma (OS) has remained stagnant in last decades, requiring the identification of novel therapeutic targets. Recently, much attention was paid to the role of squalene epoxidase (SQLE), a rate-limiting enzyme in cholesterol metabolism, in the field of onco...

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Bibliographic Details
Main Authors: Qi Song, Lina He, Jing Feng
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Molecular and Cellular Probes
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0890850824000458