Impact of Endogenous Pneumococcal Hydrogen Peroxide on the Activity and Release of Pneumolysin

<i>Streptococcus pneumoniae</i> is the leading cause of community-acquired pneumonia. The pore-forming cholesterol-dependent cytolysin (CDC) pneumolysin (PLY) and the physiological metabolite hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) can greatly increase the...

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Bibliographic Details
Main Authors: Jasmin Bazant, Benjamin Ott, Martina Hudel, Torsten Hain, Rudolf Lucas, Mobarak Abu Mraheil
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/15/10/593