Nicotinamide-based agglomerates of ibuprofen: formulation, solid state characterization and evaluation of tableting performance with in-silico investigation

Nicotinamide-based agglomerates of ibuprofen: formulation, solid state characterization and evaluation of tableting performance with in-silico investigation

Abstract Background The objective of the present investigation was to obtain directly compressible agglomerates of ibuprofen with nicotinamide by a quasi-emulsification solvent diffusion technique. Ibuprofen-nicotinamide agglomerates were prepared by quasi-emulsification solvent diffusion technique...

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Bibliographic Details
Main Authors: Prerna Hemant Sidwadkar, Nitin Hindurao Salunkhe, Kailas Krishnat Mali, Vijay Bapu Metkari, Durgesh Paresh Bidye
Format: Article
Language:English
Published: SpringerOpen 2023-08-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Ibuprofen
Nicotinamide
Agglomerates
Dissolution rate
Quasi-emulsification method
Molecular docking
Online Access:https://doi.org/10.1186/s43094-023-00521-0

Internet

https://doi.org/10.1186/s43094-023-00521-0

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