The RXFP2-PLC/PKC signaling pathway mediates INSL3-induced regulation of the proliferation, migration and apoptosis of mouse gubernacular cells

The RXFP2-PLC/PKC signaling pathway mediates INSL3-induced regulation of the proliferation, migration and apoptosis of mouse gubernacular cells

Abstract Background Testicular hypoplasia can affect the sexual and reproductive ability in adulthood, and even increase the risk of cancer. Abnormal development of the gubernaculum is one of the important factors of testicular hypoplasia. Therefore, a study of the structure and function of the gube...

Full description

Bibliographic Details
Main Authors: Shouxing Duan, Xuewu Jiang, Jianhong Li, Maxian Fu, Zhuo Li, Yiyi Cheng, Yangmu Zhuang, Ming Yang, Wenfeng Xiao, Hongyan Ping, Yao Xie, Xiaojun Xie, Xuan Zhang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cellular & Molecular Biology Letters
Subjects:
INSL3
RXFP2
PLC/PKC
Gubernaculum
Signaling pathway
Online Access:https://doi.org/10.1186/s11658-023-00433-0

Internet

https://doi.org/10.1186/s11658-023-00433-0

Similar Items