Transcriptomic and phenotype analysis revealed the role of rpoS in stress resistance and virulence of a novel ST3355 ESBL-producing hypervirulent Klebsiella pneumoniae isolate

Transcriptomic and phenotype analysis revealed the role of rpoS in stress resistance and virulence of a novel ST3355 ESBL-producing hypervirulent Klebsiella pneumoniae isolate

IntroductionAn extended-spectrum beta-lactamase (ESBL)-hypervirulent Klebsiella pneumoniae (HvKP) strain HKE9 was isolated from the blood in an outpatient.MethodsThe effect of the global regulatory factor RpoS on antimicrobial resistance, pathogenicity, and environmental adaptability was elucidated....

Full description

Bibliographic Details
Main Authors: Yi Zhou, Yue Cheng, Tianyou Ma, Jun Wang, Shaoru Li, Jingdan Wang, Lei Han, Xinyao Hou, Xinxin Ma, Sijin Jiang, Pu Li, Jia Lv, Bei Han, Rong Da
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
hypervirulent Klebsiella pneumoniae
ESBLs
pathogenomic
rpoS
virulence
environmental stress and disinfectants tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1259472/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1259472/full

Similar Items