Integrative Metabolomic Characterization Reveals the Mediating Effect of <i>Bifidobacterium breve</i> on Amino Acid Metabolism in a Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is commonly accompanied by global alterations in metabolic profiles, resulting in cognitive impairment and neuroinflammation in the brain. Using ultraperformance liquid chromatography-mass spectrometry, we performed integrative untargeted metabolomic analysis of metabolite a...

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Bibliographic Details
Main Authors: Guangsu Zhu, Min Guo, Jianxin Zhao, Hao Zhang, Gang Wang, Wei Chen
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/14/4/735