Hepatitis B Virus Promotes Hepatocellular Carcinoma Progression Synergistically With Hepatic Stellate Cells via Facilitating the Expression and Secretion of ENPP2

Hepatitis B Virus Promotes Hepatocellular Carcinoma Progression Synergistically With Hepatic Stellate Cells via Facilitating the Expression and Secretion of ENPP2

Background: Hepatitis B virus (HBV) infection is a major risk factor causing hepatocellular carcinoma (HCC) development, but the molecular mechanisms are not fully elucidated. It has been reported that virus infection induces ectonucleotide pyrophosphatase-phosphodiesterase 2 (ENPP2) expression, the...

Full description

Bibliographic Details
Main Authors: Wanyu Deng, Fu Chen, Ziyu Zhou, Yipei Huang, Junlong Lin, Fapeng Zhang, Gang Xiao, Chaoqun Liu, Chao Liu, Leibo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
hepatitis B virus-related hepatocellular carcinoma
prognosis
ectonucleotide pyrophosphatase-phosphodiesterase 2
hepatic stellate cells
progression
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.745990/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.745990/full

Similar Items