Molecular mechanisms of amyloid disaggregation

Molecular mechanisms of amyloid disaggregation

Introduction: Protein aggregation and deposition of uniformly arranged amyloid fibrils in the form of plaques or amorphous aggregates is characteristic of amyloid diseases. The accumulation and deposition of proteins result in toxicity and cause deleterious effects on affected individuals known as a...

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Bibliographic Details
Main Authors: Kimberly Jia Yi Low, Anandalakshmi Venkatraman, Jodhbir S. Mehta, Konstantin Pervushin
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Journal of Advanced Research
Subjects:
Amyloids
Chaperones
Disaggregation
Protein folding and misfolding
Protein aggregation
Online Access:http://www.sciencedirect.com/science/article/pii/S209012322100093X

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http://www.sciencedirect.com/science/article/pii/S209012322100093X

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