Tracing the origin of the NS1 A188V substitution responsible for recent enhancement of Zika virus Asian genotype infectivity
A recent study showed that infectivity of Zika virus (ZIKV) Asian genotype was enhanced by an alanine-to-valine amino acid substitution at residue 188 of the NS1 protein, but the precise time and location of origin of this mutation were not formally estimated. Here, we applied a Bayesian coalescent-...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
2017-09-01
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Series: | Memorias do Instituto Oswaldo Cruz |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017005008101&lng=en&tlng=en |