Investigation of Solid-State Hydrate-Anhydrous Phase Transformations of Dabigatran Etexilate Hemi-Edisylate

Investigation of Solid-State Hydrate-Anhydrous Phase Transformations of Dabigatran Etexilate Hemi-Edisylate

In this study, a dabigatran etexilate edisylate (DBE) was prepared by the reaction crystallization of dabigatran etexilate (DBG) and edisilic acid. According to single crystal X-ray diffraction (SXRD), it was revealed that two DGB were combined with one edisylate and associated with one water for DB...

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Bibliographic Details
Main Authors: Jin Feng, Changjin Lim, Sihyun Nam, Woojin Yoon, Hoseop Yun, Woo-Sik Kim, Ji-Hun An
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Crystals
Subjects:
dabigatran etexilate
salt form
polymorphs
polymorphic transformation
crystal structure
Online Access:https://www.mdpi.com/2073-4352/13/3/424

Internet

https://www.mdpi.com/2073-4352/13/3/424

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