Synthesis, crystal structures, molecular docking, and urease inhibitory activity of transition metal complexes with 2-[4-(4-fluorophenyl)piperazin-1-yl]acetic acid

Synthesis, crystal structures, molecular docking, and urease inhibitory activity of transition metal complexes with 2-[4-(4-fluorophenyl)piperazin-1-yl]acetic acid

Two novel mononuclear complexes, [Cu(L)2(H2O)]·2H2O (1) and [Ni(L)2(H2O)2] (2) (HL = 2-[4-(4-fluorophenyl)piperazin-1-yl]acetic acid) were synthesized and structurally determined by single-crystal X-ray diffraction. Their inhibitory activities were tested in vitro against jack bean urease. Molecular...

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Bibliographic Details
Main Authors: Zhi-Jian Chen, Chun-Na Xu, Jin-Long Zhu, Dan-Dan Yang, Shan-Shan Zhao, Ya-Nan Chen, Shao-Song Qian
Format: Article
Language:English
Published: Slovenian Chemical Society 2016-01-01
Series:Acta Chimica Slovenica
Subjects:
Complexes
Crystal structure
Urease inhibitor
Molecular docking
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/2109

Internet

https://journals.matheo.si/index.php/ACSi/article/view/2109

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