Mucosal and systemic immunization against tuberculosis by ISCOMATRIX nano adjuvant co-administered with alginate coated chitosan nanoparticles

Mucosal and systemic immunization against tuberculosis by ISCOMATRIX nano adjuvant co-administered with alginate coated chitosan nanoparticles

Objective(s): BCG vaccine has no longer been appreciated to immunize against tuberculosis, worldwide, so novel appropriate adjuvants have been dedicated to improve immune responses. This study aimed to evaluate the immunomodulatory effects of ISCOMATRIX as an adjuvant to stimulate potent humoral and...

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Bibliographic Details
Main Authors: Adel Najafi, Kiarash Ghazvini, Mojtaba Sankian, Leila Gholami, Sirvan Zare, Arshid Youdefi-Avarvand, Mohsen Tafaghodi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
adjuvant
chitosan
immune response
iscomatrix
nanoparticle
Online Access:https://ijbms.mums.ac.ir/article_22667_5e9cbf45793c425696386ac81eddba20.pdf

Internet

https://ijbms.mums.ac.ir/article_22667_5e9cbf45793c425696386ac81eddba20.pdf

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