Phosphoproteomic profiling of selenate-treated Alzheimer's disease model cells.

The reversible phosphorylation of proteins regulates most biological processes, while abnormal phosphorylation is a cause or consequence of many diseases including Alzheimer's disease (AD). One of the hallmarks of AD is the formation of neurofibrillary tangles (NFTs), which is composed of hyper...

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Bibliographic Details
Main Authors: Ping Chen, Lixiang Wang, Yong Wang, Shuiming Li, Liming Shen, Qiong Liu, Jiazuan Ni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259334?pdf=render