The tumor suppressor gene <it>KCTD11</it><sup><it>REN </it></sup>is regulated by Sp1 and methylation and its expression is reduced in tumors

The tumor suppressor gene <it>KCTD11</it><sup><it>REN </it></sup>is regulated by Sp1 and methylation and its expression is reduced in tumors

<p>Abstract</p> <p>A hallmark of several human cancers is loss of heterozygosity (LOH) of chromosome 17p13. The same chromosomal region is also frequently hypermethylated in cancer. Although loss of 17p13 has been often associated with <it>p53 </it>genetic alteration or...

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Bibliographic Details
Main Authors: Rinaldi Christian, Di Camillo Raffaello, Murgo Simona, Po Agnese, Capece Daria, Ciccocioppo Lucia, Zazzeroni Francesca, Mancarelli M Michela, Ferretti Elisabetta, Gulino Alberto, Alesse Edoardo
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/172

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http://www.molecular-cancer.com/content/9/1/172

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