Effects of exosomes of mesenchymal stem cells on cholesterol-induced hepatic fibrogenesis

Objective(s): Free cholesterol in the diet can cause liver fibrosis by accumulating in Hepatic stellate cells (HSCs). The rate of mortality of this disease is high worldwide and there is no definite remedy for it, but might be treated by anti-fibrotic therapies. MSCs-derived exosomes are known as th...

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Bibliographic Details
Main Authors: Mojtaba Rashidi, Emad Matour, Sajad Monjezi, Shahla Asadi Zadeh, Elham Shakerian, Sahar Sabahy, Reza Afarin
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_22277_65c4dd42d51f936b63cfc3406bbf9a3c.pdf