Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors

Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors

Homologous recombination (HR) is a DNA double-strand break (DSB) repair pathway that utilizes a homologous template to fully repair the damaged DNA. HR is critical to maintain genome stability and to ensure genetic diversity during meiosis. A specialized class of enzymes known as recombinases facili...

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Bibliographic Details
Main Authors: Andrew A. Kelso, Sarah M. Waldvogel, Adam J. Luthman, Michael G. Sehorn
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Microbiology
Subjects:
homologous recombination
DNA repair
double-strand break repair
protozoan parasites
recombination inhibitors
RAD51
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01716/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01716/full

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