Berbamine inhibits Japanese encephalitis virus (JEV) infection by compromising TPRMLs-mediated endolysosomal trafficking of low-density lipoprotein receptor (LDLR)

Berbamine inhibits Japanese encephalitis virus (JEV) infection by compromising TPRMLs-mediated endolysosomal trafficking of low-density lipoprotein receptor (LDLR)

Japanese encephalitis virus (JEV), a member of the Flavivirus genus, is an important pathogen that causes human and animal infectious diseases in Asia. So far, no effective antiviral agents are available to treat JEV infection. Here, we found that LDLR is a host factor required for JEV entry. Berbam...

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Bibliographic Details
Main Authors: Lihong Huang, Huanan Li, Zuodong Ye, Qiang Xu, Qiang Fu, Wei Sun, Wenbao Qi, Jianbo Yue
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
Subjects:
Berbamine
flavivirus
JEV
LDLR
Ca2+
TRPMLs
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.1941276

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2021.1941276

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