Detecting protein and DNA/RNA structures in cryo-EM maps of intermediate resolution using deep learning

It is challenging to extract structural information from EM density maps at intermediate or low resolutions. Here, the authors present Emap2sec+, a program for detecting nucleotides and protein secondary structures in EM density maps at 5 to 10 Å resolution.

Bibliographic Details
Main Authors: Xiao Wang, Eman Alnabati, Tunde W. Aderinwale, Sai Raghavendra Maddhuri Venkata Subramaniya, Genki Terashi, Daisuke Kihara
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22577-3