Computational design of α-amylase from Bacillus licheniformis to increase its activity and stability at high temperatures

Computational design of α-amylase from Bacillus licheniformis to increase its activity and stability at high temperatures

The thermostable α-amylase derived from Bacillus licheniformis (BLA) has multiple advantages, including enhancing the mass transfer rate and by reducing microbial contamination in starch hydrolysis. Nonetheless, the application of BLA is constrained by the accessibility and stability of enzymes capa...

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Bibliographic Details
Main Authors: Shuai Fan, Xudong Lü, Xiyu Wei, Ruijie Lü, Cuiyue Feng, Yuanyuan Jin, Maocai Yan, Zhaoyong Yang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Protein engineering
Molecular dynamics
α-amylase
Thermostability
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000308

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http://www.sciencedirect.com/science/article/pii/S2001037024000308

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