Analysis of Kojic Acid Derivatives as Competitive Inhibitors of Tyrosinase: A Molecular Modeling Approach

Analysis of Kojic Acid Derivatives as Competitive Inhibitors of Tyrosinase: A Molecular Modeling Approach

Tyrosinases belong to the functional copper-containing proteins family, and their structure contains two copper atoms, in the active site, which are coordinated by three histidine residues. The biosynthesis of melanin in melanocytes has two stages depending on the actions of the natural substrates L...

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Bibliographic Details
Main Authors: Richelly Cardoso, Renan Valente, Clauber Henrique Souza da Costa, João Lidio da S. Gonçalves Vianez, Kauê Santana da Costa, Fábio Alberto de Molfetta, Cláudio Nahum Alves
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
skin cancer
melanogenesis
tyrosinase
kojic acid derivatives
molecular docking
molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/26/10/2875

Internet

https://www.mdpi.com/1420-3049/26/10/2875

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