Experimental and Hirshfeld Surface Investigations for Unexpected Aminophenazone Cocrystal Formation under Thiourea Reaction Conditions via Possible Enamine Assisted Rearrangement

Experimental and Hirshfeld Surface Investigations for Unexpected Aminophenazone Cocrystal Formation under Thiourea Reaction Conditions via Possible Enamine Assisted Rearrangement

Considering the astounding biomedicine properties of pharmaceutically active drug, 4-aminophenazone, also known as 4-aminoantipyrine, the work reported in this manuscript details the formation of novel cocrystals of rearranged 4-aminophenazone and 4-nitro-<i>N</i>-(4-nitrobenzoyl) benzam...

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Bibliographic Details
Main Authors: Asma Khurshid, Aamer Saeed, Tuncer Hökelek, Umama Taslim, Madiha Irfan, Saba Urooge Khan, Aneela Iqbal, Hesham R. El-Seedi
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Crystals
Subjects:
cocrystal
aminophenazone
thiourea reaction conditions
single crystal
Hirshfeld surface analysis
plausible mechanism
Online Access:https://www.mdpi.com/2073-4352/12/5/608

Internet

https://www.mdpi.com/2073-4352/12/5/608

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