Intratumoural spatial distribution of S100B + folliculostellate cells is associated with proliferation and expression of FSH and ERα in gonadotroph tumours

Intratumoural spatial distribution of S100B + folliculostellate cells is associated with proliferation and expression of FSH and ERα in gonadotroph tumours

Abstract Folliculostellate cells are S100B-expressing cells with numerous functions in the normal anterior pituitary. These cells have also been identified in pituitary neuroendocrine tumours (PitNETs), where their precise role remains elusive. Here, we aimed to build a refined cartography of S100B-...

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Bibliographic Details
Main Authors: Mirela Diana Ilie, Alexandre Vasiljevic, Marie Chanal, Nicolas Gadot, Laura Chinezu, Emmanuel Jouanneau, Ana Hennino, Gérald Raverot, Philippe Bertolino
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Acta Neuropathologica Communications
Subjects:
Tumour heterogeneity
Folliculostellate cells
S100B + cells
Tumour microenvironment
Gonadotroph adenoma
Online Access:https://doi.org/10.1186/s40478-022-01321-y

Internet

https://doi.org/10.1186/s40478-022-01321-y

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