Human RAD51 Protein Forms Amyloid-like Aggregates <i>In Vitro</i>

Human RAD51 Protein Forms Amyloid-like Aggregates <i>In Vitro</i>

RAD51 is a central protein of homologous recombination and DNA repair processes that maintains genome stability and ensures the accurate repair of double-stranded breaks (DSBs). In this work, we assessed amyloid properties of RAD51 <i>in vitro</i> and in the bacterial curli-dependent amy...

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Bibliographic Details
Main Authors: Daniel V. Kachkin, Kirill V. Volkov, Julia V. Sopova, Alexander G. Bobylev, Sergei A. Fedotov, Sergei G. Inge-Vechtomov, Oxana V. Galzitskaya, Yury O. Chernoff, Aleksandr A. Rubel, Anna Y. Aksenova
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
RAD51
protein aggregation
protein fibrils
amyloid
X-ray diffraction
functional amyloids
Online Access:https://www.mdpi.com/1422-0067/23/19/11657

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https://www.mdpi.com/1422-0067/23/19/11657

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