Mycobacterium tuberculosis PE/PPE proteins enhance the production of reactive oxygen species and formation of neutrophil extracellular traps

Mycobacterium tuberculosis PE/PPE proteins enhance the production of reactive oxygen species and formation of neutrophil extracellular traps

IntroductionNeutrophil granulocytes predominate in the lungs of patients infected with Mycobacterium tuberculosis (Mtb) in earlier stages of the disease. During infection, neutrophils release neutrophil extracellular traps (NETs), an antimicrobial mechanism by which a DNA-backbone spiked with antimi...

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Bibliographic Details
Main Authors: María García-Bengoa, Marita Meurer, Matthias Stehr, Ayssar A. Elamin, Mahavir Singh, Wulf Oehlmann, Matthias Mörgelin, Maren von Köckritz-Blickwede
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium tuberculosis
Mtb
PE18
PE31
PPE26
neutrophil extracellular traps (NETs)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1206529/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1206529/full

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