Epigenetics of Myotonic Dystrophies: A Minireview

Epigenetics of Myotonic Dystrophies: A Minireview

Myotonic dystrophy type 1 and 2 (DM1 and DM2) are two multisystemic autosomal dominant disorders with clinical and genetic similarities. The prevailing paradigm for DMs is that they are mediated by an <i>in trans</i> toxic RNA mechanism, triggered by untranslated CTG and CCTG repeat expa...

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Bibliographic Details
Main Authors: Virginia Veronica Visconti, Federica Centofanti, Simona Fittipaldi, Elisa Macrì, Giuseppe Novelli, Annalisa Botta
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
myotonic dystrophies (DMs)
epigenetics
methylation
chromatin remodeling
microRNAs (miRNAs)
Online Access:https://www.mdpi.com/1422-0067/22/22/12594

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https://www.mdpi.com/1422-0067/22/22/12594

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