Three-dimensional identification of microvascular pathology and neurovascular inflammation in severe white matter hyperintensity: a case report

Abstract White matter hyperintensities (WMH) are the most prevalent markers of cerebral small vessel disease (SVD), which is the major vascular risk factor for dementia. Microvascular pathology and neuroinflammation are suggested to drive the transition from normal-appearing white matter (NAWM) to W...

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Bibliographic Details
Main Authors: Gemma Solé-Guardia, Matthijs Luijten, Bram Geenen, Jurgen A. H. R. Claassen, Geert Litjens, Frank-Erik de Leeuw, Maximilian Wiesmann, Amanda J. Kiliaan
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-55733-y