A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials

A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials

Abstract Background Dengue is a neglected tropical disease, for which no therapeutic agents have shown clinical efficacy to date. Clinical trials have used strikingly variable clinical endpoints, which hampers reproducibility and comparability of findings. We investigated a delta modified Sequential...

Full description

Bibliographic Details
Main Authors: Angela McBride, Nguyen Lam Vuong, Nguyen Van Hao, Nguyen Quang Huy, Ho Quang Chanh, Nguyen Thi Xuan Chau, Nguyen Minh Nguyet, Damien K. Ming, Nguyen Thanh Ngoc, Phung Tran Huy Nhat, Nguyen Thanh Phong, Luong Thi Hue Tai, Phan Vinh Tho, Dinh The Trung, Dong Thi Hoai Tam, Huynh Trung Trieu, Ronald Bertus Geskus, Martin J. Llewelyn, C. Louise Thwaites, Sophie Yacoub
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Infectious Diseases
Subjects:
Dengue
Shock
SOFA
Modified SOFA
Delta SOFA
Clinical trial endpoint
Online Access:https://doi.org/10.1186/s12879-022-07705-8

Internet

https://doi.org/10.1186/s12879-022-07705-8

Similar Items