Inhibition of Caspase-11-Mediated Pyroptosis Alleviates Acute Kidney Injury Associated with Severe Acute Pancreatitis in Rats

Inhibition of Caspase-11-Mediated Pyroptosis Alleviates Acute Kidney Injury Associated with Severe Acute Pancreatitis in Rats

Background: Acute kidney injury (AKI) is a common complication in patients with severe acute pancreatitis (SAP). Caspase-11-mediated pyroptosis is essential for the progression of multiple diseases, but its role in SAP-induced AKI remains unknown. Aims: This research investigated whether caspase-11-...

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Bibliographic Details
Main Authors: Yang Shao, Chang Li, Yingjian Jiang, Hongbo Li, Xuefei Tang, Zhaoyu Gao, Dianliang Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-01-01
Series:Journal of Investigative Surgery
Subjects:
caspase-11
pyroptosis
severe acute pancreatitis
acute kidney injury
wedelolactone
Online Access:http://dx.doi.org/10.1080/08941939.2022.2142868

Internet

http://dx.doi.org/10.1080/08941939.2022.2142868

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