Transfer of Invitro CD4 + T Cells with Hypomethylation of Perforin Promoter into Rats’ Abdomens Causes Autoimmune Emphysema

Our previous study suggested that hypomethylation of perforin promoter of CD4 + T cells might be involved in the pathogenesis of autoimmune emphysema of rats. Whether transfer of this kind of cells hypomethylated in vitro into naive immunocompetent rats also results in emphysema is unknown yet. To t...

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Bibliographic Details
Main Authors: Jia-jia Liu, Lin Liu, Hong-hong Mu, Jia-yi Li, Lin Xu, Yao-yao Wu, Ben-xue Li, Ye Zhang, Xiang-yan Zhang, Xian-wei Ye, Cheng Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:COPD
Subjects:
Online Access:http://dx.doi.org/10.1080/15412555.2022.2072720