Antioxidant and antibacterial activities of 5-mercapto(substitutedthio)-4-substituted-1,2,4-triazol based on nalidixic acid: A comprehensive study on its synthesis, characterization, and In silico evaluation

Antioxidant and antibacterial activities of 5-mercapto(substitutedthio)-4-substituted-1,2,4-triazol based on nalidixic acid: A comprehensive study on its synthesis, characterization, and In silico evaluation

This study introduces a series of novel Alkyl thio-1,2,4-triazole (4a-p) and mercapto-1,2,4-triazole (3a-d) compounds derived from nalidixic acid. The synthesis was streamlined, involving interactions between nalidixic acid hydrazide and various isothiocyanates to yield cyclic and alkyl(aryl) sulfid...

Full description

Bibliographic Details
Main Authors: Ibrahim Mhaidat, Sojoud Banidomi, Fadel Wedian, Rahaf Badarneh, Hasan Tashtoush, Waleed Almomani, Ghassab M. Al-Mazaideh, Naiyf S. Alharbi, Muthu Thiruvengadam
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Antioxidant
Antimicrobial
Isothiocyanate
Alkyl halide
Nalidixic acid
In silico
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402404235X

Internet

http://www.sciencedirect.com/science/article/pii/S240584402404235X

Similar Items