Bayesian integrative analysis of epigenomic and transcriptomic data identifies Alzheimer's disease candidate genes and networks.

Biomedical research studies have generated large multi-omic datasets to study complex diseases like Alzheimer's disease (AD). An important aim of these studies is the identification of candidate genes that demonstrate congruent disease-related alterations across the different data types measure...

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Bibliographic Details
Main Authors: Hans-Ulrich Klein, Martin Schäfer, David A Bennett, Holger Schwender, Philip L De Jager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007771