MET-Targeting Anticancer Drugs—De Novo Design and Identification by Drug Repurposing
The Met protein is a cell surface receptor tyrosine kinase predominantly expressed in epithelial cells. Aberrant regulation of <i>MET</i> is manifested by numerous mechanisms including amplification, mutations, deletion, fusion of the <i>MET</i> proto-oncogene, and protein ov...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-07-01
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Series: | Drugs and Drug Candidates |
Subjects: | |
Online Access: | https://www.mdpi.com/2813-2998/2/3/31 |