Doxycycline Alters the Porcine Renal Proteome and Degradome during Hypothermic Machine Perfusion

Doxycycline Alters the Porcine Renal Proteome and Degradome during Hypothermic Machine Perfusion

Ischemia-reperfusion injury (IRI) is a hallmark for tissue injury in donation after circulatory death (DCD) kidneys. The implementation of hypothermic machine perfusion (HMP) provides a platform for improved preservation of DCD kidneys. Doxycycline administration has shown protective effects during...

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Bibliographic Details
Main Authors: Leonie van Leeuwen, Leonie H. Venema, Raphael Heilig, Henri G. D. Leuvenink, Benedikt M. Kessler
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Current Issues in Molecular Biology
Subjects:
renal transplantation
ischemia/reperfusion injury
machine perfusion
proteomics
degradomics
Online Access:https://www.mdpi.com/1467-3045/44/2/39

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https://www.mdpi.com/1467-3045/44/2/39

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